Cardio-Vascular Disease (CVD) remains the leading cause of death among diabetic patients. Aim: To compare the CVD prevalence and assess the CVD risks between females and males diabetic patients. Methods: All patients with diabetes who attended the outpatient clinicat National Diabetes Hospital from Sep 2013 to April 2022 were interviewed and examined, demography data about their ages, smoking habits, Body Mass Index measures, history of prior cardiovascular events, blood pressure measurement and fasting lipid profile were collected, these data were analyzed Statistically by SPP. Results:1060patients have completed the study,689 females representing (65%), themean age was 54.07±14.5 years, Bodyweight of the studied patients ranged from 44 kg to 186 kg(85.66 ±1.73) underweight was seen in 1.4%,normal BMI seen in 15.8%,and 828 (78.55%) have uncontrolled body weight. The duration of diabetes varying from newly diabetes (20.3%)to more than ten years duration(37.9%).(72%) of the patients were Non-smokers, (27.2%) had uncontrolled blood pressure. Uncontrolled dyslipidaemia was seen in (7.1 %), uncontrolled hyperglycaemia was seen in (62.9 %), and Established CVD was positive in (23.2%). Those who are54 to74 years of age had multiple CVD risk factors were female patients, with long standing of history of diabetes (more than 10 years), had uncontrolled hyperglycemia (HBA1c>10g%), uncontrolled body weight, uncontrolled blood pressure, and dyslipidemia as well. Conclusion: This study shows that female diabetic patients have higher CVD risk factors than malediabetic patients sharing the same age and the same duration of diabetes. Themale diabetic Smokers have a significant CVD risk. Recommendation: increase the awareness of females' diabetic patients regarding the early
symptoms of cardiovascular diseases, the importance of preventive measures against CVD risks
of diabetes, and the importance of regular follow up especially in females.