Moringaoleiferais a highly valued plant distributed in many countries of the tropic and subtropics.
Moringaoleiferaleaves are a potential source of phytochemical ingredients claimed to have analgesic
property. Theanalgesic drugs lacking the side effect as alternative to nonsteroidal anti-inflammatory
drugs (NSAIDs) and opiates are in demand by the society. The aim of this study is undertaken to
evaluate the analgesic activity of Moringaoleiferausing thermal induced pain by tail flick test. The
study was done using experimental models (albino rats). The albino rats were divided into four
groups, each group consisting of 3 rats. Group I: (Control dH2O given orally at 2 ml/kg body weight);
Group II:( Standard Panadol given 100 mg/kg orally); Group III, IV, (aqueous extract of
Moringaoleifera(AMO) 50, 100 mg/kg, respectively). The AMO were administered orally 1 hour before
the experiments. For central analgesic effect was screened using tail flick test.The AMO leaf showed
significant (P < 0.01) analgesic activity withboth 50,100mg/kg at60 min with a mean rank ranging
(3.43±0.29), (4.30±0.23) respectively when comparison with control and standard that with mean rank
ranging (2.13±0.08), (2.66±0.08) respectively.The AMO exhibited analgesic activity in tail flick test
showing its both central and peripheral analgesic actions. This study confirms the traditional uses of
M. oleiferain treatment of diseases, particularly those related to pain and inflammation.