Helicobacter pylori (H. Pylori) is a gram-negative spiral bacterium that colonizes only the mucous
layer of the human stomach. They are found in about half of the world's population. H. pylori
infection is currently considered one of the most common bacterial infections in humans. The
discovery of H. pylori has revolutionized the treatment of many gastrointestinal illnesses. This
bacterium has been identified as a major cause of several gastrointestinal illnesses, including gastric
adenocarcinoma, gastric ulcer disease and mucosal-related tissue. Some studies are consistently
showing the association between H. pyloriinfection and gastric cancer. The study aimed to establish
evaluating the prevalence of H. pylori infection with gastroenteritis in Mesllata-Libya. The serum
samples were collected from 69 patients with gastrointestinal disorders, all of them have been livingin
Mesllata-Libya. And each sample screened against anti H. pylori IgG to evaluate the prevalence of H.
pylori infection in those patients. A total of 69 sera samples werecollected and analyzed. The first
group was aged (10-25) years contains 15 patients are females only. Whereas 11 (73.3%) of them were
infected. The second group was aged (26-40) years contains 26 patients, 12 males (46.15%) and 14
females (53.85%). Eight (66.7%) of males were infected while 4 (33.3%) were non-infected, 13 (92.86%)
of females were infected and one patient (6.14%) was non-infected.
The third group was the elderly aged (>41) years contains 28 patients, 15 males (53.57%) and 13
females (46.43%). Eleven (73.3%) of males were infected while 4 (26.7) were non-infected, 10 (76.9%) of
females were infected and 3 patient (23.1%) were non-infected.
Based on the findings of this study,no significant correlation was observed between gender and
agewith H. pylori infection, infection with H. pylori is highly prevalent in the Libyan patient with