Neurofibromatosis type 1 (NF1), also known as von Recklinghausen’as disease, is the most
common type of NF. The hallmarks of NF1 are the multiple café-au-lait macules and associated
with cutaneous neurofibromas. The condition is called segmental NF1 when clinical features are
limited to one area of the body. We report the case of a 23 years old male patient who presented
with leftbreastdisfigurement.Physical examination showed severe disfigurement (fibrosis
swelling) over left breast with multiple different size café-au-lait spots. Ophthalmology and
MRIbrain showed no evidence of glioma. The diagnosis of plexiform neurofibromatosis based
on clinical &histopathological findings.
Keywords: Plexiform, Neurofibromatosis, Disability.