Abstract:
Allium sativum (Garlic) and Nigella sativa (Black cumin) are widely used as food seasoning or traditional medications in many countries. Their effects on STZ induced type 1 diabetes in rats were compared. Type 1 diabetes induced to rats by injecting STZ. The oil extracts of A. sativum and N. sativa were peritoneally injected daily at concentrations of 10 mg/kg, 20 mg/kg for A. sativum and 7 mg/kg or 14 mg/kg for N. sativa. Compared to the untreated group, the two groups treated with A. sativum and the two groups treated with N. sativa showed marked recoveries in some physiological aspects. The data showed marked improvements in body weights for all treated groups especially the groups treated with A. sativum, and after four weeks body weights were improving whereas body weights for untreated group were decreased. FBG levels in the group treated with 10mg/kg A-

download pdf button 11