The purpose of this study was to evaluate the difference in serum chromium and
magnesium levels between diabetic and control groups, and to determine the correlations between
these elements and serum glucose in patients with type 2 diabetes mellitus. Fifty patients suffering
from type 2 diabetes and 50 controls were selected randomly. The level of serum chromium,
magnesium and fasting plasma glucose were measured and compared between the two groups.
Correlations of serum Cr, Mg and glucose were conducted. Serum magnesium was significantly
lower in diabetic group compared with the control group (Mean ± SD): 19.067 ± 2.156 compared to
42.82 ± 2.15 n mol/l (P = 0.00). The serum level of Cr (0.11172 ± 0.054664) of the test group was
similarly matched with healthy group (0.08094 ± 0.039764), ( p = 0.214). Significant but negative
correlations were shown between Mg and plasma glucose (P = 0.00, r = -3.85). No significant and
negative correlation between Cr and plasma glucose (P= 0.214, r = -0.190). There is trace element
metabolism disorder in patients with type 2 diabetes mellitus (Magnesium) and serum level of
Chromium of the test group was similarly matched with healthy group.
Keywords: diabetes mellitus, glucose level, chromium, magnesium

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